By Dr. The average age at diagnosis is nine to eleven years. Some dogs with AGASACA present with signs related to the mass itself, such as a swelling in the perianal region, a mass palpated on routine rectal exam, scooting, or straining to defecate.
Cytology from fine needle aspirate of an anal sac adenocarcinoma. Typical epithelial cell clustering is noted. Anal gland adenocarcinoma AGA also known as apocrine gland anal sac carcinoma adenocarcinoma or anal sac adenocarcinoma is an uncommon cancer that arises from the apocrine glands in the walls of the anal sacs.
The perianal region of the dog contains several glands, specifically apocrine sweat glands, which are normally responsible for emptying their secretions into the lumen of the anal sacs. Anal sac apocrine gland adenocarcinoma is locally invasive and typically affects one anal sac; however, bilateral tumors can occur. Figure 1: Apocrine gland adenocarcinoma of the left anal sac.
Back to Fact Sheets. Download PDF. This is described as an uncommon tumour but we do seem to see a significant number of patients with this disease, no doubt partly due to this being a special interest in our clinic.
Other treatment modalities include radiotherapy and chemotherapy, but the role of these treatments has not been clearly determined yet. Pre-operative medical support is provided as required. In particular, severe hypercalcaemia of malignancy HM; i.
These are paired glands located on either side of the rectal opening. Anal glands are sweat glands that contain a brown, malodorous liquid that is eliminated upon defecation. AGASACAs are locally invasive tumors with a high rate of metastasis to regional lymph nodes including sublumbar and medial iliac lymph nodes inside the abdomen and inguinal nodes located in the groin.
The anal glands are small sacs found on either side of the anal opening of your dog. The lining of the sacs produces a small amount of liquid, which is eliminated each time your dog defecates. The development of a tumor in this area can be significant; even with the presence of a small growth there is the definite possibility that the tissues will be invaded and the cancer will spread metastasize.
Dogs and cats can function normally without these scent glands. Cancer can develop in the anal sac glands in dogs, but rarely in cats. In most cases, this tumor affects only one anal sac, but occasionally both left and right sacs are affected.
The obnoxious substance coming out of the anal glands is supposed to help dogs mark their territory when they defecate. In reality, anal glands can cause all kinds of problems in dogs and occasionally in cats. They can get blocked, infected or even turn into cancer.
Anal gland cancer is fairly uncommon, but is very serious when it occurs as it produces malignant tumors. Regular yearly check ups with your vet will include a rectal examination, which can detect a tumor early on. They produce a little liquid that has a scent unique to your dog though, to you and I it just smells plain unpleasant.